DNA Structures of DNA triplexes
A new paper by Jiahui Zhang in the computational group of Professors Roland and Sagui explore how specific repetitive DNA sequences leads to DNA triplex structures responsible for diseases.
Zhang, JH, Fakharzadeh, A, Pan, F, Roland, C, Sagui, C, Atypical structures of GAA/TTC trinucleotide repeats underlying Friedreich’s ataxia: DNA triplexes and RNA/DNA hybrids. Nucleic Acids Researchm, 48(17) 9899-9917, DOI:10.1093/nar/gkaa665